Additive Manufacturing and Printing Approaches for the Development of Pharmaceutical Dosage Forms with Improved Biopharmaceutical Attributes

Author:

Ahmad Farhan J.1,Kawish Syed M.1,Sharma Shwetakshi2,Almalki Waleed H.3,Alghamdi Saad4,Afzal Obaid5,Kazmi Imran6,Altamimi Abdulmalik S.A.5,Al-Abbasi Fahad A.6,Beg Sarwar1

Affiliation:

1. Department of Pharmacy, Nanomedicine Research Lab, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India

2. Department of Pharmacy, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India

3. Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

4. Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia

5. Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, AlKharj, 11942, Saudi Arabia

6. Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia

Abstract

Abstract: Pharmaceutical industry is moving ahead with the future experiencing an innovation in drug development through the introduction of personalized medicine technologies. Instead of adapting the dose which a patient actually needs, they were adapted to the manufacturer’s dose. Now patient specific or customized method of dosing and dose combinations has superior insistence rather than the standard mass medicines. Printing technology has gained interest during the last years for manufacturing of personalized dosage forms. For manufacturing of personalized drug products three dimensional printing (3DP) has expanded to the pharmaceutical industry. With the approval of first 3DP product an unprecedented opportunity for the discovery of new compounds and technologies has arisen. In this article, we have re-evaluated various printing technology and its utilization in personalized medicines. Further, we also discussed its history, advantages, challenges and various types of printing technologies with advantages and limitations particularly in the area of pharmaceutical research.

Funder

Deanship of Scientific Research at Umm Al-Qura University

Publisher

Bentham Science Publishers Ltd.

Subject

Clinical Biochemistry,Pharmacology

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