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Application of Nucleic Acid Nanomaterials in the Treatment of Endocrine and Metabolic Diseases

  • Published:2023-05 Issue:5 Volume:24 Page:385-392
  • ISSN:1389-2002
  • Container-title:Current Drug Metabolism
  • language:en
  • Short-container-title:CDM

Author:

Zhu Qiang12ORCID,Xie Yuping23ORCID,Fu Ting23ORCID,Shi Chengji12ORCID,Bai Long23ORCID,Liu Lin12ORCID,Xiao Jingang123ORCID

Affiliation:

1. Department of Oral and Maxillofacial Surgery, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou 646000, China

2. Luzhou Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China

3. Department of Oral Implantology, The Affiliated Stomatological Hospital of Southwest Medical University, Luzhou, 646000, China

Abstract

Abstract: Endocrine and metabolic diseases are the most prevalent chronic diseases globally, posing the greatest hazard to human health. Although various medications are applied in treating endocrine and metabolic illnesses, numerous obstacles exist to overcome. Nucleic acid nanomaterials are novel materials synthesized and engineered in the laboratory. In this case, Nucleic acids are employed as non-biological nanomaterials instead of serving as carriers of genetic information in live cells. Because of their high biocompatibility and editability, nucleic acid nanomaterials were frequently employed in disease diagnosis and therapy. In this review, recent developments and new viewpoints on nucleic acid nanomaterials are highlighted in the fields of diabetes mellitus and other endocrine and metabolic diseases.

Funder

National Natural Science Foundation of China

Special Project for Local Science and Technology Development Guided by the Central Government of Sichuan Province

Project of Science & Technology Department of Sichuan Province

Open Project of State Key Laboratory of Oral Disease Research

Joint project of Luzhou Municipal People's Government and Southwest Medical University

Key Program of Southwest Medical University

Project of Stomatological Institute of Southwest Medical University

Publisher

Bentham Science Publishers Ltd.

Subject

Clinical Biochemistry,Pharmacology

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