Targeting Nanotechnology and Nutraceuticals in Obesity: An Updated Approach

Abstract

Hypothesis: This review article represents a brief layout of the risk factors and pathophysiology responsible for obesity, customary treatment strategies, and nanotechnology-based nutraceutical for therapeutics of obesity. Experiments: An exhaustive search of the literature was done for this purpose, using Google Scholar, PubMed, and ScienceDirect databases. A study of the literature was conducted using publications published in peer-reviewed journals between the years 2000 and 2022. Findings: This was revealed that risk factors responsible for obesity were genetic abnormalities, environmental, and socio-economic factors. Number of research articles published between 2000 and 2022 were based on phytoconstituents based nanoformulation for obesity therapeutics and therefore, have been systematically compiled in this review. Various nutraceuticals like Garcinia cambogia, quercetin, resveratrol, capsaicin, Capsicum, Curcuma longa, Camella Sinensis, Zingiber officinalis, Citrus aurantium, Aegle marmelos, Coffea canephora, Asparagus officinalis, Gardenia jasminoides, Catha edulis, Clusia nemroisa, Rosmarinus officinalis, Cirsium setidens, Betula platyphylla, Tripterygium wilfordi possessing anti-obesity actions are discussed in this review along with their patents, clinical trials as well as their nanoformulation available. Conclusion: This review illustrates that the nanotechnology have a great propensity to impart promising role in the delivery of phytochemicals and nutraceuticals in management of obesity conditions and other related disorders.