Affiliation:
1. Department of Emergency and Organ Transplantation - Urology, Andrology, and Kidney Transplantation Unit - University of Bari, Italy
Abstract
Gonadotropin-releasing hormone (GnRH) is the focus of the scientific debate for the treatment of
hypogonadotropic hypogonadism. Sexual maturation and reproductive function depend on the pulsatile secretion
of GnRH that are mainly congenital and may or may not be associated with other genetic anomalies or syndromes.
Clinical manifestations include a wide range of metabolic, endocrine, and psychologic dysfunctions. The
following manuscript focuses on the effects of GnRH therapy on fertility and cognitive abilities, aiming to investigate
the current level of evidence for this treatment regimen. Current literature has been reviewed with the aim
of highlighting the key findings on these two aspects.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
Cited by
5 articles.
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