Affiliation:
1. School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF, United Kingdom
Abstract
Abstract:
Urban pollution is one of the main problems encountered worldwide, with a major impact on public
health as well as the environment. The health impact of urban pollution is not limited to respiratory conditions
but also encompasses major skin problems, including irritation, skin ageing, and skin cancer. Toxic gases and
particulate matter are the main pollutants that exhibit extensive local variability. The aforementioned pollutants
are small particles that attach to the skin or penetrate it, enhancing free radicals’ production inside the inner skin
layers. This urges the need to propose cosmetic products that help prevent and/or minimise pollutants’ effects
on the skin, whether irritation, ageing, and cancer. Furthermore, intrinsic and extrinsic factors contribute to skin
irritation and ageing. Intrinsic factors are within skin factors and include genetic and physiological characteristics
of individuals. Moreover, extrinsic factors comprise environmental factors such as humidity, temperature,
and smoke. Subsequently, active ingredients with anti pollutant properties addressed the intrinsic and extrinsic
factors by four mechanisms: free radical neutralisation, film-forming ability, skin barrier enhancement, and fortification.
Such ingredients include vitamin A derivatives, vitamin C derivatives, carbohydrates, and plantbased
products. Yet, very limited studies have evaluated the effectiveness of the aforementioned active ingredients
against irritation or ageing, which should be considered in future work.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology