Feeding Pattern, Circadian Rhythm, and Immune Function: What do we know about?

Author:

Lira Fábio Santos12ORCID,Estanislau Thiago Barros3,Kruger Karsten4,Rosa-Neto José Cesar5,Padilha Camila S.1,Gonçalves Daniela Caetano3,Minuzzi Luciele Guerra12

Affiliation:

1. Department of Physical Education, Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Universidade Estadual Paulista (UNESP), Presidente Prudente, Brazil

2. Faculty of Sports Science and Physical Education, Research Center for Sports and Physical Activity, University of Coimbra, Coimbra, Portugal

3. Department of Biosciences, Universidade Federal de São Paulo (UNIFESP), Campus Baixada Santista, Santos, São Paulo, Brazil

4. Department of Exercise Physiology and Sports Therapy, Institute of Sports Science, University of Giessen, Giessen, Germany

5. Department of Cell Biology and Development, Immunometabolism Research Group, Institute of Biomedical Science, University of São Paulo, São Paulo, Brazil

Abstract

Abstract: Feeding pattern is related to health status or chronic diseases, and this depends on the individual’s eating habits. Feeding organized with the right time to start and end during the day, promotes an internal biological rhythm, favoring molecular synchronization of the clock genes, which impose an effect on metabolism and immune cells, creating a physiological response related to a healthy profile. On the other hand, a feeding pattern disorganized, without the right time to start and end eating during the day, might lead to nonsynchronization of the clock genes, a disruption condition, which is related to chronic diseases, such as obesity and diabetes type 2. A strategy that should be adopted to favor molecular synchronization is time-restricted eating (TRE), which can organize the initial and end of the eating patterns during the day. Our review points out some cues that suggest TRE as an efficient strategy for healthy profile and can be a good intervention for the treatment of chronic diseases.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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