An Overview of Copper Nanoparticles: Synthesis, Characterisation and Anticancer Activity

Author:

Naikoo Gowhar1,Al-Mashali Fatema2,Arshad Fareeha3,AL-Maashani Naema2,Hassan Israr U.4,AL Baraami Zamzam2,Faruck Lukmanul H.3,Qurashi Ahsanulhaq5,Ahmed Waqar6,Asiri Abdullah M.6,Aljabali Alaa A.7,Bakshi Hamid A.8,Tambuwala Murtaza M.9

Affiliation:

1. Department of Mathematics and Sciences, College of Arts and Applied Sciences, Dhofar University, Salalah 211, Oman

2. Department of Chemical Engineering, College of Engineering, Dhofar University, Salalah 211, Oman

3. Department of Biochemistry, Aligarh Muslim University, U.P., India

4. College of Engineering, Dhofar University, Salalah 211, Oman

5. Department of Urology, Masonic Cancer Center, University of Minnesota, MN55455, United Arab Emirates

6. School of Mathematics and Physics, College of Science, University of Lincoln, Lincoln, LN6 7TS, United Kingdom

7. Department of Chemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia

8. Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Yarmouk University, Irbid 566, Jordan

9. School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, County Londonderry, BT52 1SA, Northern Ireland,, United Kingdom

Abstract

: In this review, we summarised the different methods for copper nanoparticle synthesis, including green methods. We highlighted that the synthesis of the copper nanoparticles from green sources is preferable as they serve as stable and reducing entities. Furthermore, we critically reviewed the effectiveness of copper- based nanoparticles in oncogenic treatments emphasizing breast, lung, colorectal, and skin cancers. Finally, we have summarised the recent progress made in copper-based nanoparticles and their applications to amplify and rectify present cancer treatment options. The synthesis, characterization, stabilization, and functionalization techniques of various copper-based nanoparticles have also been highlighted in each section. In conclusion, the review provides the outlook of copper nanoparticles in cancer diagnostics and therapeutics.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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