Molecular Hydrogen Application in Stroke: Bench to Bedside

Author:

Huang Lei1ORCID,Lenahan Cameron2ORCID,Boling Warren1ORCID,Tang Jiping2ORCID,Zhang John H.1ORCID

Affiliation:

1. Department of Neurosurgery, Loma Linda University, Loma Linda, CA92354, United States

2. Center for Neuroscience Research, Loma Linda University School of Medicine, Loma Linda, CA, 92324, United States

Abstract

Stroke is a major cause of mortality and morbidity worldwide. Effective treatments are limited. Molecular hydrogen is emerging as a novel medical gas with therapeutic potential for various neurological diseases, including stroke. We reviewed the experimental and clinical findings of the effects of molecular hydrogen therapy in stroke patients and models. The underlying neuroprotective mechanisms against stroke pathology were also discussed.

Funder

Loma Linda University

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology

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