Affiliation:
1. College of Pharmacy and Biological Engineering, Chengdu University, Chengdu, China
2. Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu, China
Abstract
Cancer stem cells (CSCs) show self-renewal ability and multipotential differentiation, like normal stem
or progenitor cells, and which proliferate uncontrollably and can escape the effects of drugs and phagocytosis by
immune cells. Traditional monotherapies, such as surgical resection, radiotherapy and chemotherapy, cannot
eradicate CSCs, however, combination therapy may be more effective at eliminating CSCs. The present review
summarizes the characteristics of CSCs and several promising combination therapies to eradicate them.
Funder
National Natural Science Foundation of China
Applied Basic Research Programs of Sichuan Province Science and Technology Department
Scientific Research Innovation Group Foundation of Educational Committee of Sichuan Province
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
Cited by
8 articles.
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