Benzimidazole Derivatives as Potential Antimicrobial and Antiulcer Agents: A Mini Review-Reference-Cited by-同舟云学术

Benzimidazole Derivatives as Potential Antimicrobial and Antiulcer Agents: A Mini Review

Published:2019-09-25 Issue:16 Volume:19 Page:1292-1297
ISSN:1389-5575
Container-title:Mini-Reviews in Medicinal Chemistry
language:en
Short-container-title:MRMC

Author:

Ganie Ali Mohd¹,Dar Ayaz Mahmood²,Khan Fairooz Ahmad³,Dar Bashir Ahmad³

Affiliation:

1. Department of Chemistry, Bundelkhand University, Jhansi U.P, India

2. Department of Chemistry, Government Degree College Kulgam 192231, J&K, India

3. Department of Chemistry, Government Degree College (Boys) Sopore 193201, India

Abstract

:Here in we report the number of strategies for the synthesis of differently substituted benzimidazole derivatives. The protocols involved in the syntheses of these derivatives were one-pot or multi-component. The characterization studies of these derivatives were carried by using different spectroscopic techniques (1H NMR, 13C NMR and MS) and elemental analyses. The biological screening studies revealed that these benzimidazole derivatives show potential antibacterial as well as antifungal behavior. These benzimidazole derivatives not only depicted potential antiulcer properties but also showed moderate to good anticancer/cytotoxic behavior against different cancer cell lines.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

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