A Mini-Review on Pyridazine Analogs: Chemical and Pharmacological Potentials

Author:

Asif Mohammad1ORCID,Alghamdi Saad2ORCID

Affiliation:

1. Glocal School of Pharmacy, Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh, India

2. Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al‒Qura University, Makkah, 21955, Saudi Arabia

Abstract

Abstract: The pyridazinone derivatives have diverse biological potential and are easily synthesized. Due to this, researchers and chemists have paid attention to the design and development of novel and effective bioactive compounds. The substituted pyridazines have shown a wide range of pharmacological activities, such as analgesic, anti-inflammatory, antibacterial, antifungal, anticonvulsant, antidepressant, antianxiety, antitubercular, anti-malarial, anticancer, anti-HIV, platelet inhibitory, hypotensive, cardiotonic, etc. In the current circumstances, it can be concluded that pyridazinone derivatives have great prospects, which remain to be revealed.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

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