Therapeutic Effects of Berberine against Urological Cancers: Biological Potentials Based on Cellular Mechanisms-Reference-Cited by-同舟云学术

Therapeutic Effects of Berberine against Urological Cancers: Biological Potentials Based on Cellular Mechanisms

Published:2023-11-06 Issue: Volume:23 Page:
ISSN:1566-5240
Container-title:Current Molecular Medicine
language:en
Short-container-title:CMM

Author:

Savoji Ali Bozorg¹,Kaheni Yasamin²,Rezaei Pouria³,Farkhondeh Tahereh⁴,Pourhanifeh Mohammad Hossein⁵,Samarghandian Saeed⁶

Affiliation:

1. Student Research Committee, Islamic Azad University, Tehran Medical Branch, Tehran, Iran

2. Student Research Committee, Islamic Azad University, Mashhad Medical Branch, Mashhad, Iran

3. Student Research Committee, Tehran University of Medical Sciences, Tehran, Iran

4. Department of Toxicology and Pharmacology, School of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran

5. Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran

6. Healthy Ageing Research Centre, Neyshabur University of Medical Sciences, Neyshabur, Iran

Abstract

Abstract: Urological cancers, including prostate, kidney, and bladder cancer are problematic human diseases worldwide. Current strategies for the treatment of these cancers are chemotherapy, radiotherapy, surgery, or a combination of mentioned therapies. Due to the high mortality and morbidity rate of urological cancers and possible side effects of available standard treatments, searching for more effective and safe treatments is a critical issue. The beneficial properties of natural compounds, such as berberine, have been widely investigated in human diseases. Moreover, the anticancer potential of this agent has been extensively documented, especially in experimental studies. In this review, we have tried to discuss the effect of berberine against urological cancers, focusing on cellular and molecular mechanisms.

Publisher

Bentham Science Publishers Ltd.

Subject

Molecular Biology,Molecular Medicine,General Medicine,Biochemistry