Affiliation:
1. Department of Biotechnology,DDU Gorakhpur University, Gorakhpur,Gorakhpur,India,
Abstract
: Neurodegenerative disease such as Alzheimer’s disease, Parkinson’s
disease, Huntington’s disease, amyotrophic lateral sclerosis, frontotemporal dementia,
and the spinocerebellar ataxias is major health threat specifically in the elderly
population. Currently, the disease diagnosis and progression is tracked through the
clinical estimation which only gives a rough estimate of the disease severity. So the
biomarkers serve as an essential tool in the disease diagnosis and disease progression.
High-throughput omics-based technologies have facilitated the discovery of new
biomarkers. The analytic methods underlying the basic omics-based technologies,
genomics, transcriptomics, and metabolomics are now been extensively useful in the
identification of novel biomarkers. These new candidate biomarkers are helpful in the
clinical management of neurological disorders.
Publisher
BENTHAM SCIENCE PUBLISHERS
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