Nitric oxide: A Brief History of Discovery and Timeline of its Research

Author:

Ghasemi Asghar1,Kashfi Khosrow2

Affiliation:

1. Shahid Beheshti University of Medical Sciences,,Endocrine Physiology Research Center, Research Institute for Endocrine Sciences,Tehran,Iran

2. Department of Molecular, Cellular and Biomedical Sciences, Sophie Davis School of Biomedical Education, City University of New York School of Medicine, New York, NY10031, USA

Abstract

Nitric oxide (NO) plays a critical role in many physiological and pathological functions in the human body. Following the discovery in 1986-1987 that endothelium-derived relaxing factor (EDRF) is NO, the number of NO-based publications within all fields of medicine has increased exponentially. This report provides a brief historical view of NO-based research, emphasizing the events in the last two decades of the 20th century.

Publisher

BENTHAM SCIENCE PUBLISHERS

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