Protein-Peptide Docking: An Initiation to Discover Therapeutic Peptides

Abstract

The in-silico study on protein-peptide docking involves initiating the biomolecular interaction to identify compatible peptides with antibacterial properties. The current research elucidates a computational module for the discovery. The proteinpeptide docking of marine peptides against the marine bacteria and the gills of teleost fish in CABS-DOCK resulted in a compatible docked structure with the highest accuracy. Protein-peptide docking resulted in maximum compatibility for “ELLVDLL” derived from marine bacteria than “FIHHIIGGLFSVGKHIHGLIHGH” derived from the tapaila gills of teleost fish concerning receptors of resistant bacterial strains.