Cell Signaling Pathways in Cancer-Reference-Cited by-同舟云学术

Cell Signaling Pathways in Cancer

Published:2023-04-18 Issue: Volume: Page:242-272
ISSN:
Container-title:Molecular Targets and Cancer Therapeutics (Part 1)
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Author:

Al-Saihati Hajir A.¹,Al-Toub Mashael²,Sharaf Hanaa I.³,Singh Manjari⁴,Ansari Mohd. Nazam⁵,Bin Saeedan Abdulaziz⁵

Affiliation:

1. University of Hafr Al-Batin,Department of Clinical Laboratory Sciences,Hafr Al-Batin,Saudi Arabia,

2. King Saud University,Department of Clinical Laboratory Sciences,Riyadh,Saudi Arabia,

3. King Saud Medical City,Riyadh,Saudi Arabia,

4. Assam University,Department of Pharmaceutical Sciences,Assam,India,

5. Prince Sattam Bin Abdulaziz University,College of Pharmacy,Alkharj,Saudi Arabia,

Abstract

Cancer is characterized by atypical cell proliferation that has the possibility of dissemination to different body parts. Tumor formation is influenced by genetic mutations and environmental pollutants. The formation and progression of malignancies have been linked to a diversity of molecular paths. The JAK/STAT, NOTCH, PI3K/AKT pathway, mitogen-activated protein kinase (MAPK), transforming growth factor-beta (TGF-beta) (TGF-), NF-B, and Wnt signaling pathways will be highlighted in this chapter. Cancer development has been linked to various changes to the signaling pathways' components. As a result, various initiatives to target signaling pathways in order to build distinct treatment lines have been approved. In this chapter, we discuss the role of signal transduction in cancer-associated processes and how their targets influence the behavior of the tumor cells.<br>

Publisher

BENTHAM SCIENCE PUBLISHERS

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