Affiliation:
1. Institute of Medicine, Medical Research Center, Jishou University, Hunan, China
2. Institute of Pharmaceutical Sciences, Jishou University, Hunan, China.
Abstract
Abstract:
Gap junction (GJ) is a special cell membrane structure composed of connexin. Connexin
is widely distributed and expressed in all tissues except differentiated skeletal muscle, red
blood cells, and mature sperm cells, which is related to the occurrence of many genetic diseases
due to its mutation. Its function of regulating immune response, cell proliferation, migration, apoptosis,
and carcinogenesis makes it a therapeutic target for a variety of diseases. In this paper, the
possible mechanism of its action in nervous system-related diseases and treatment are reviewed.
Funder
National Natural Science Foundation of Hunan Province
Innovation Project of Postgraduate Research of Hunan Province
Innovation and Entrepreneurship Training Program of College Students
Publisher
Bentham Science Publishers Ltd.
Subject
Biochemistry,General Medicine,Structural Biology
Cited by
1 articles.
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