Potential benefits of Tricetin in medicine for the treatment of cancers and other health-related disorders: Medicinal importance and therapeutic benefit

Abstract

Background: Medicinal plants have been used in medicine for the treatment of numerous diseases due to their medicinal properties and pharmacological activities. Popularity of herbal based drugs in the health sector has been increasing due to patient compliance and cost effectiveness. Herbal drugs derived from plant and animal source have been used in the Ayurvedic, Homeopathic, and Naturopathic system of medicine. Medicinal plants have been used as fuel, clothing, shelter and food material in worldwide since very early age. Phytoconstituents are pure plant chemicals found in different parts of the plant material. Flavonoids are important class of phytochemical found in medicinal plants and their derived products. Methods: In order to know the biological importance of tricetin, in the present investigation scientific data of tricetin in respect to their medicinal importance and pharmacological activities were collected and analyzed. Literature database such as Google, PubMed, Science Direct and Scopus has been searched using term tricetin and flavonoid. All the scientific information has been collected from these databases to know the biological importance of tricetin. Analytical data of tricetin have been also collected and analyzed in the present work to know the isolation, separation and identification procedure of trice Results: Scientific data analysis of different research work revealed the presence of tricetin in Triticum dicoccum, Lathyrus pratensis, Eucalyptus globules, Thuja occidentalis and Metasequoia glyptostroboides. Scientific data analysis signified biological importance of tricetin against different form of cancerous disorders, human osteosarcoma, glioblastoma multiforme, human breast adenocarcinoma, human non‑small cell lung cancer and liver cancer. Scientific data analysis also signified biological potential of tricetin against inflammation, neurodegenerative diseases, atherosclerosis, diabetes and respiratory syncytial virus infection. Scientific data analysis revealed the biological importance of tricetin against multidrug resistance and free radicals. Conclusions: Scientific data analysis revealed biological importance and pharmacological activities of tricetin against various form of human disorders including cancer, inflammation, neurodegeneration, atherosclerosis and diabetes.