Affiliation:
1. Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh,
India
Abstract
Abstract::
Globally, there are around 50 million Alzheimer's disease sufferers worldwide, a number that
is expected to double every five years and reach 152 million by 2050. Traditional drugs for cognitive
impairment are only palliative and do not cure the disease. Alzheimer's disease is characterised by
memory and language loss, as well as difficulties with visual orientation and greater executive function.
The present study aimed to examine various causes, mechanisms, and roles of different herbal components
in the treatment of Alzheimer’s disease. Since ancient times, several different plants have been utilised
to improve memory and treat various dementia-related issues. These anti-AD plants include a wide
taxonomic range due to acetyl choline esterase inhibition, antioxidant capacity, neuroprotection, mitochondrial
energy restoration, and/or precipitated protein clearance. Secondary metabolites of these medicinal
plants may be used to treat AD. AADvac1 is an active vaccination that stimulates an immune response
by attacking numerous critical epitopes in pathogenic tau variants, thereby preventing tau aggregation
and reducing the development of neurofibrillary tangles. Herbal plants are widely used because of
their perceived effectiveness, safety, and low cost. To summarise, the evidence supporting the use of
herbal components is promising, but more work is needed.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry