Hypothetical Proteins as Predecessors of Long Non-coding RNAs-Reference-Cited by-同舟云学术

Hypothetical Proteins as Predecessors of Long Non-coding RNAs

Published:2020-10-22 Issue:7 Volume:21 Page:531-535
ISSN:1389-2029
Container-title:Current Genomics
language:en
Short-container-title:CG

Author:

Malik Girik¹^ORCID,Agarwal Tanu²^ORCID,Raj Utkarsh²,Sundararajan Vijayaraghava Seshadri¹,Bandapalli Obul Reddy³^ORCID,Suravajhala Prashanth¹^ORCID

Affiliation:

1. Bioclues.org, Kukatpally, Hyderabad, 500072, India

2. NIIT University, NH8, Delhi- Jaipur Highway, District Alwar, Neemrana, Rajasthan 301705, India

3. Hopp Children's Cancer Center [KiTZ], Heidelberg, Germany

Abstract

Hypothetical Proteins [HP] are the transcripts predicted to be expressed in an organism, but no evidence of it exists in gene banks. On the other hand, long non-coding RNAs [lncRNAs] are the transcripts that might be present in the 5’ UTR or intergenic regions of the genes whose lengths are above 200 bases. With the known unknown [KU] regions in the genomes rapidly existing in gene banks, there is a need to understand the role of open reading frames in the context of annotation. In this commentary, we emphasize that HPs could indeed be the predecessors of lncRNAs.

Publisher

Bentham Science Publishers Ltd.

Subject

Genetics(clinical),Genetics

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