Drug Design Tools - In Silico, In Vitro and In Vivo ADME/PK Prediction and Interpretation: Is PK in Monkey An Essential Part of a Good Human PK Prediction?
Author:
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,General Medicine
Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Understanding Pharmacokinetic Disconnect in Preclinical Species for 4-Aminoquinolines: Consequences of Low Permeability and High P-glycoprotein Efflux Ratio on Rat and Dog Oral Pharmacokinetics;Journal of Pharmaceutical Sciences;2020-10
2. Extended Clearance Classification System (ECCS) and its Utility in Predicting Clearance Rate-Determining Step in Drug Discovery;Oral Bioavailability Assessment;2017-05-05
3. Drug Routes of Excretion;Oral Bioavailability Assessment;2017-05-05
4. The Utility of Eccs as a Roadmap to Improve Oral Bioavailability of New Molecular Entities: Industrial Perspective;Oral Bioavailability Assessment;2017-05-05
5. Comprehensive Assessment of Human Pharmacokinetic Prediction Based on In Vivo Animal Pharmacokinetic Data, Part 2: Clearance;The Journal of Clinical Pharmacology;2013-01-24
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