Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding-Reference-Cited by-同舟云学术

Intracholecystic Papillary-tubular Neoplasm (ICPN) of the Gallbladder: A Case Report Focusing on an Unexpected Pathological Finding

Published:2023-10-25 Issue: Volume:19 Page:
ISSN:1574-8928
Container-title:Recent Patents on Anti-Cancer Drug Discovery
language:en
Short-container-title:PRA

Author:

Pesce Antonio¹,Sani Valentina¹,Gaban Alba²,Fabbri Nicolò¹,Tilli Massimo³,Gafà Roberta²,Feo Carlo Vittorio¹

Affiliation:

1. Section of General Surgery, University of Ferrara, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy

2. Department of Morphology, Surgery and Experimental Medicine, University of Ferrara and S. Anna University Hospital, Ferrara, Italy

3. Department of Radiology, Azienda USL of Ferrara, Via Valle Oppio 2, 44023 Lagosanto (FE), Italy

Abstract

Background: Intracholecystic papillary neoplasms (ICPNs) represent a rare benign entity characterized by intraluminal polypoid lesions in the gallbladder. The incidence of ICPNs ranges from 0.4% to 0.61% in all gallbladder specimens. Case Presentation: In this report, we present a case of a young Caucasian woman who underwent elective laparoscopic cholecystectomy due to gallbladder polyps. The histological examination revealed the presence of an intracholecystic papillary neoplasm (ICPN) with a tubulopapillary growth pattern, exhibiting gastric morphology and displaying both low and high-grade dysplasia. A thorough review of the existing literature was conducted, with a specific focus on the histological features. Conclusion: A comprehensive understanding of neoplastic polyps of the gallbladder is still limited. Pathological examination of these lesions is crucial for identifying key features that can influence patient outcomes and survival.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology (medical),Cancer Research,Drug Discovery,Oncology,General Medicine