Determinants of Medication Adherence among Jordanian Patients with End Stage Kidney Disease

Abstract

Background End stage kidney disease (ESKD) requires complex medical management. To ensure the success of management plan, patient’s adherence to medication is fundamental. However, adherence to medication is challenging for patients with ESKD. Objective This study aimed to describe adherence to medication and to identify demographic and clinical determinants in Jordanian patients with ESKD. Methods Cross-sectional correlational design was performed using a sample of 188 patients with ESKD who attended haemodialysis units in five hospitals in Amman between March and June 2021. Medication adherence was measured using Morisky Medication Adherence Scale (MMAS). Results The mean age of the participants was 50.9 years (SD=15.64), more than half of the participants were males 109 (58.0%) and were non-smokers 115 (61.2%). The mean score of the MMAS was 5.18 (SD=2.024) which indicates high prevalence of inadequate adherence to medication. Younger age, longer duration on hemodialysis, and higher number of medications were risk factors for inadequate adherence to medication among patients with ESKD. Conclusion ESKD patients who are younger in age, have longer duration on hemodialysis, and have higher number of medications should be targeted as they have medication adherence challenges. Those patients should be taken into consideration when planning and developing interventions to enhance medication adherence in patients with ESKD.