Stem Cells as a Resource for Treatment of Infertility-related Diseases

Author:

Wang Jing1,Liu Chi2,Fujino Masayuki2,Tong Guoqing1,Zhang Qinxiu3,Li Xiao-Kang2,Yan Hua1

Affiliation:

1. Reproductive Center, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China

2. Division of Transplantation Immunology, National Research Institute for Child Health and Development, Tokyo, Japan

3. Department of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China

Abstract

Worldwide, infertility affects 8-12% of couples of reproductive age and has become a common problem. There are many ways to treat infertility, including medication, intrauterine insemination, and in vitro fertilization. In recent years, stem-cell therapy has raised new hope in the field of reproductive disability management. Stem cells are self-renewing, self-replicating undifferentiated cells that are capable of producing specialized cells under appropriate conditions. They exist throughout a human’s embryo, fetal, and adult stages and can proliferate into different cells. While many issues remain to be addressed concerning stem cells, stem cells have undeniably opened up new ways to treat infertility. In this review, we describe past, present, and future strategies for the use of stem cells in reproductive medicine.

Funder

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Molecular Biology,Molecular Medicine,General Medicine,Biochemistry

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