Role of Natural Plant Products Against Hemagglutinin-esterase (HE) of Human Coronavirus-Reference-Cited by-同舟云学术

Role of Natural Plant Products Against Hemagglutinin-esterase (HE) of Human Coronavirus

Published:2022-05 Issue:2 Volume:3 Page:
ISSN:2665-9786
Container-title:Current Nutraceuticals
language:en
Short-container-title:CNT

Author:

Siddique Yasir Hasan¹^ORCID,I. Mantasha²,Shahid Mohd.²,Naz Falaq¹

Affiliation:

1. Department of Zoology, Faculty of Life Sciences, Drosophila Transgenic Laboratory, Section of Genetics, Aligarh Muslim University, Aligarh, 202002, Uttar Pradesh, India

2. Department of Chemistry, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India

Abstract

Background: COVID-19 has spread worldwide and become a great cause of economic and social loss. Due to the non-availability of effective medicine/drug, its control has become a dif-ficult task. Objective: In the present study, the effect of some selected natural plant products was studied on the Hemagglutinin-esterase of the human coronavirus by performing molecular docking. Methods: Molecular docking study for some selected natural plant products against Hemagglutinin-esterase (HE) of human coronavirus was performed using the HEX 8.0.0 software. Results: The free binding energy ranged from -298.14 to -161, with that of curcumin being the highest. Conclusions: The results suggest that the natural plant products could act as possible anti-viral agents and may be used as natural therapeutic agents.

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine

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