Affiliation:
1. Department of Pharmacy, IEC College of Eng & Tech. Gautam Buddha Nagar, India
2. ABESIT College of Pharmacy,
Ghaziabad, India
Abstract
Abstract:
Over the years, natural compounds have become a significant advancement in cancer
treatment, primarily due to their effectiveness, safety, bio-functionality, and wide range of molecular
structures. They are now increasingly preferred in drug discovery due to these attributes.
These compounds, whether occurring naturally or with synthetic modifications, find applications
in various fields like biology, medicine, and engineering.
:
While chemotherapy has been a successful method for treating cancer, it comes with systemic
toxicity. To address this issue, researchers and medical practitioners are exploring the concept of
combinational chemotherapy. This approach aims to reduce toxicity by using a mix of natural
substances and their derivatives in clinical trials and prescription medications.
:
Among the most extensively studied natural anticancer compounds are quercetin, curcumin, vincristine,
and vinblastine. These compounds play crucial roles as immunotherapeutics and
chemosensitizers, both as standalone treatments and in combination therapies with specific
mechanisms. This review article provides a concise overview of the functions, potentials, and
combinations of natural anticancer compounds in cancer treatment, along with their mechanisms
of action and clinical applications
Publisher
Bentham Science Publishers Ltd.