Affiliation:
1. Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences,
Prayagraj 211007, Uttar Pradesh, India
Abstract
Background:
Herbal plant-based products and their derived phytochemicals have been
used in the complementary and alternative systems of medicine for the treatment of human
disorders. Vegetables, fruits, seeds, nuts, coffee, tea, and wine contain significant amounts of
coumarin class phytochemicals. Coumarin is found to be present in cassia leaf oil, cinnamon bark
oil, lavender oil, and microorganism-derived drugs.
Methods:
Scientific databases, such as Google Scholar, Science Direct, Scopus, and PubMed, have
been searched to collect the scientific information regarding meranzin and meranzin hydrate in the
present work in order to know their medicinal importance and pharmacological activities in the
medicine. Pharmacological activity data of meranzin and meranzin hydrates has been thoroughly
studied from scientific databases and analyzed in the present work to evaluate their biological
potential against human disorders. Analytical data on meranzin and meranzin hydrates have been
also collected and analyzed in the present work to know the importance of analytical techniques for
the standardization of plant material.
Results:
Scientific data analysis revealed the biological potential of meranzin and meranzin
hydrates against human health complications. Meranzin was found to be present in the Fructus
aurantii, Triphasia trifolia, Cnidium monnieri, and Murraya exotica. Scientific data analysis
revealed the biological potential of meranzin and meranzin hydrates in the medicine due to their
anti-depressant, anti-fibrotic, anti-proliferative, anti-atherosclerosis, and anti-bacterial activities.
Further scientific data analysis revealed the biological effectiveness of meranzin and meranzin
hydrates on neuroinflammation, intestinal motility, and various forms of enzymes. Furthermore,
pharmacokinetic parameters for meranzin and meranzin hydrates were also investigated in the
present work. Chromatography techniques used for the analysis were also summarized and
discussed to examine the importance of isolation, separation, and quantification of meranzin and
meranzin hydrates.
Conclusion:
Present study will facilitate scientists in the development of effective medicine from
meranzin and meranzin hydrates against the various human health complications.
Publisher
Bentham Science Publishers Ltd.
Subject
General Earth and Planetary Sciences,General Environmental Science