Quality of Life and Depression Assessment in Patients with Acute Coronary Syndrome: A Cross-Sectional Study

Author:

Varghese Treesa P.1,Kumar P. R Anand Vijaya2

Affiliation:

1. Department of Pharmacy Practice, Yenepoya Pharmacy College and Research Centre (Yenepoya deemed to be University), Deralakatte, Mangalore, India

2. Department of Pharmacology, JSS Academy of Higher Education and Research Centre (JSSAHER), JSS College of Pharmacy, Ooty, India

Abstract

Purpose: Acute Coronary Syndrome (ACS) is currently the leading cause of death in industrialized countries. Morbidity after ACS includes physical and mental disorders affecting the patient’s whole life situation and Quality of Life (QoL). The main aim of the study was to assess QoL and depression among post-ACS patients. Methods: This was a cross-sectional observational study. A total of 112 patients who fulfilled the inclusion criteria were included in this study. A semi-structured questionnaire was administered to the patients to collect data from the patients. In this study, men and women aged 18 - 80 with ACS; patients diagnosed with Non-ST Segment Elevated Myocardial Infarction (NSTEMI) or STEMI or Angina Pectoris were included. Patients with severe mental, and physical illness and dementia were excluded from the study. QoL and depression assessment was done by RAND 36-Item Health Survey and Hamilton Depression Rating scale, respectively. Results: Among 112 post-ACS patients, 78 patients were males, and 38 patients were females. The mean age of the study population was 64.25 ± 9.029 and with most individuals in the category of 61 - 70 years. The majority of study populations were married (71.5%) and lived with their families (92.9%). In this study group, 42.9 % of the population reported at least high school education (SSLC) and 54.5% were full-time employees. Most of the patients (91.1%) were taking the medication regularly, while 55.4% of patients reported regular compliance with the follow-up. This study identified that, among various factors, older age, female gender, lower income, unemployment, low education status, poor compliance with medication, and depressive symptoms led to poor QoL. Conclusion: This study confirms a negative correlation between depressive symptoms and QoL. This study’s results reveal the magnitude of depression that is prevalent in the primary health care clinic that goes undiagnosed and unmanaged. Hence, it is recommended to properly screen depressive symptoms in ACS patients. Therefore, concurrently, better QoL can be achieved by managing both depression and ACS.

Funder

University Grants Commission, Government of India

Publisher

Bentham Science Publishers Ltd.

Subject

Cardiology and Cardiovascular Medicine,Pharmacology,Hematology,Molecular Medicine,General Medicine

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