Affiliation:
1. Department of Pharmacy Practice, Yenepoya Pharmacy College and Research Centre (Yenepoya deemed to be University),
Deralakatte, Mangalore, India
2. Department of Pharmacology, JSS Academy of Higher Education and Research
Centre (JSSAHER), JSS College of Pharmacy, Ooty, India
Abstract
Purpose:
Acute Coronary Syndrome (ACS) is currently the leading cause of death in industrialized countries. Morbidity after ACS includes physical and mental disorders affecting the
patient’s whole life situation and Quality of Life (QoL). The main aim of the study was to assess
QoL and depression among post-ACS patients.
Methods:
This was a cross-sectional observational study. A total of 112 patients who fulfilled the
inclusion criteria were included in this study. A semi-structured questionnaire was administered to
the patients to collect data from the patients. In this study, men and women aged 18 - 80 with ACS;
patients diagnosed with Non-ST Segment Elevated Myocardial Infarction (NSTEMI) or STEMI or
Angina Pectoris were included. Patients with severe mental, and physical illness and dementia were
excluded from the study. QoL and depression assessment was done by RAND 36-Item Health Survey and Hamilton Depression Rating scale, respectively.
Results:
Among 112 post-ACS patients, 78 patients were males, and 38 patients were females. The
mean age of the study population was 64.25 ± 9.029 and with most individuals in the category of 61
- 70 years. The majority of study populations were married (71.5%) and lived with their families
(92.9%). In this study group, 42.9 % of the population reported at least high school education
(SSLC) and 54.5% were full-time employees. Most of the patients (91.1%) were taking the medication regularly, while 55.4% of patients reported regular compliance with the follow-up. This study
identified that, among various factors, older age, female gender, lower income, unemployment, low
education status, poor compliance with medication, and depressive symptoms led to poor QoL.
Conclusion:
This study confirms a negative correlation between depressive symptoms and QoL.
This study’s results reveal the magnitude of depression that is prevalent in the primary health care
clinic that goes undiagnosed and unmanaged. Hence, it is recommended to properly screen depressive symptoms in ACS patients. Therefore, concurrently, better QoL can be achieved by managing
both depression and ACS.
Funder
University Grants Commission, Government of India
Publisher
Bentham Science Publishers Ltd.
Subject
Cardiology and Cardiovascular Medicine,Pharmacology,Hematology,Molecular Medicine,General Medicine
Reference28 articles.
1. Fowler M.B.; Beta-blockers in heart failure. Do they improve the quality as well as the quantity of life? Eur Heart J 1998,19(Suppl. P),17-25
2. Lespérance F.; Frasure-Smith N.; Depression and coronary artery disease: Time to move from observation to trials. CMAJ 2003,168(5),570-571
3. Kiessling A.; Henriksson P.; Perceived cognitive function is a major determinant of health related quality of life in a non-selected population of patients with coronary artery disease--a principal components analysis. Qual Life Res 2004,13(10),1621-1631
4. Megari K.; Quality of life in chronic disease patients. Health Psychol Res 2013,1(3),e27
5. Gierlaszyńska K.; Pudlo R.; Jaworska I.; Byrczek-Godula K.; Gąsior M.; Tools for assessing quality of life in cardiology and cardiac surgery. Kardiochir Torakochirurgia Pol 2016,13(1),78-82
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