Potential Drugs for the Treatment of COVID-19: Synthesis, Brief History and Application-Reference-Cited by-同舟云学术

Potential Drugs for the Treatment of COVID-19: Synthesis, Brief History and Application

Published:2021-12-07 Issue:3 Volume:13 Page:184-202
ISSN:2589-9775
Container-title:Current Drug Research Reviews
language:en
Short-container-title:CDRR

Author:

Uddin Ekhlass¹,Islam Raisul¹,Ashrafuzzaman ¹,Bitu Nur Amin¹,Hossain Md. Saddam²,Islam ABM Nazmul³,Asraf Ali¹,Hossen Faruk¹,Mohapatra Ranjan K⁴,Kudrat-E-Zahan Md.¹

Affiliation:

1. Department of Chemistry, Rajshahi University, Rajshahi 6205, Bangladesh

2. Department of Chemistry, Begum Rokeya University, Rangpur, Bangladesh

3. Chemistry Discipline, Khulna University, Khulna-9208, Bangladesh

4. Department of Chemistry, Government College of Engineering, Keonjhar, Odisha, India

Abstract

Coronaviruses (CoVs) belong to the Betacoronavirus group, an unusually large RNA genome characterized by club-like spikes that project from their surface. An outbreak of a novel coronavirus 2019 (nCOVID-19) already showed a unique replication strategy and infection that has posed significant threat to international health and the economy around the globe. Scientists around the world are investigating few previously used clinical drugs for the treatment of COVID-19. This review provides synthesis and mode of action of recently investigated drugs like Chloroquine, Hydroxychloroquine, Ivermectin, Selamectin, Remdesivir, Baricitinib, Darunavir, Favipiravir, Lopinavir/ ritonavir and Mefloquine hydrochloride that constitute an option for COVID-19 treatment.

Publisher

Bentham Science Publishers Ltd.

Subject

Psychiatry and Mental health

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