Emerging Evidence for Neuropsycho-Consequences of COVID-19

Author:

Li Jingwen1,Long Xi2,Zhang Qing3,Fang Xi3,Fang Fang4,Lv Xuefei4,Zhang Dandan4,Sun Yu4,Li Na3,Hu Shaoping4,Lin Zhicheng5,Xiong Nian1

Affiliation:

1. Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

2. Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

3. Wuhan Red Cross Hospital, Wuhan, Hubei, China

4. Department of Radiology, Wuhan Red Cross Hospital, Wuhan, Hubei, China

5. Laboratory of Psychiatric Neurogenomics, McLean Hospital; Harvard Medical School; Belmont, MA 02478, United States

Abstract

: The pandemic novel coronavirus disease (COVID-19) has become a global concern in which the respiratory system is not the only one involved. Previous researches have presented the common clinical manifestations including respiratory symptoms (i.e., fever and cough), fatigue and myalgia. However, there is limited evidence for neurological and psychological influences of SARS-CoV-2. In this review, we discuss the common neurological manifestations of COVID-19 including acute cerebrovascular disease (i.e., cerebral hemorrhage) and muscle ache. Possible viral transmission to the nervous system may occur via circulation, an upper nasal transcribrial route and/or conjunctival route. Moreover, we cannot ignore the psychological influence on the public, medical staff and confirmed patients. Dealing with public psychological barriers and performing psychological crisis intervention are an important part of public health interventions.

Funder

Hubei medical research project

The Youth Science and Technology Morning Light Program of Wuhan City

Natural Science Foundation of Hubei Province

National Natural Science Foundation of China

National Key R&D Program of China

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology (medical),Psychiatry and Mental health,Neurology (clinical),Neurology,Pharmacology,General Medicine

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