Insight Into Bioactive Hydrogels for Wound Healing and Drug Delivery Systems

Author:

Li Jing1ORCID,Chen Qinhua2ORCID,Wang Jin1ORCID,Pan Xiaoyan1ORCID,Zhang Jie1ORCID

Affiliation:

1. School of Pharmacy, Health Science Center, Xi\'an Jiaotong University, Xi’an 710061, China

2. Department of Pharmacy, Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen 518101, China

Abstract

: Hydrogels are hydrophilic but water-soluble polymer systems with a three-dimensional network structure. They can absorb large amounts of water and maintain their shape and remain soft. The high-moisturizing properties, good biocompatibility, and controlled biodegradability of hydrogels have allowed them to be widely used in wound dressing, tissue engineering, controlled drug delivery systems, and other fields. This article reviews the most widely used antibacterial gel dressings for wound healing in recent years and focuses on the application of an environmentally responsive intelligent hydrogel delivery system. Finally, the development prospects and challenges of hydrogel wound dressings are forecasted.

Funder

National Natural Science Foundation of China

Natural Science Basic Research Plan in Shaanxi Province of China

Fundamental Research Funds for the Central Universities

Bao'an TCM Development Foundation

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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