Affiliation:
1. School of Chemistry, Chemical Engineering & Life Science, Wuhan University of Technology, Wuhan, China
Abstract
As a new type of nanomaterials, the gold nanoclusters (AuNCs) perform many
special physical and chemical properties, such as large Stokes shift, relatively simple preparation,
good water solubility, low toxicity, and good biocompatibility, which make
them show infinite potential in various fields, especially in cancer treatment. In recent
years, great progress has been made in the preparation, functionalization, and biomedical
applications of the AuNCs. In this article, the latest research progress and synthesis methods
of the AuNCs have been summarized, emphasizing the preparation using the “bottom-
up” synthesis strategy. Furthermore, we introduced the in vivo pharmacokinetic performance
of the AuNCs. In the last part, we exemplified the applications of the AuNCs
in biomedicine, including photothermal therapy (PTT), bioimaging, drug delivery, and radiotherapy
sensitization, which further confirmed the great potential of the AuNCs in tumor
treatment.
Funder
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
7 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献