Goniothalamin-Related Styryl Lactones: Isolation, Synthesis, Biological Activity and Mode of Action-Reference-Cited by-同舟云学术

Goniothalamin-Related Styryl Lactones: Isolation, Synthesis, Biological Activity and Mode of Action

Published:2020-01-08 Issue:41 Volume:26 Page:7372-7451
ISSN:0929-8673
Container-title:Current Medicinal Chemistry
language:en
Short-container-title:CMC

Author:

Pilli Ronaldo Aloise¹,de Toledo Ian¹,Meirelles Matheus Andrade¹,Grigolo Thiago Augusto¹

Affiliation:

1. Department of Organic Chemistry, Institute of Chemistry, University of Campinas, Campinas, Brazil

Abstract

: This review covers the chemistry and biological aspects of goniothalamin-related styryl lactones isolated from natural sources. This family of secondary metabolites has been reported to display diverse uses in folk medicine, but only a limited number of these compounds have been throughly investigated regarding their biological profile. Herein, we cover the goniothalamin-related styryl lactones having a C6-C3-C4 framework which appeared in the literature for the first time in the period 2000-2017, and the reports on the synthesis, biological activity and mechanism of action which were published from 2007-2017.

Funder

Foundation for Research Support of the State of São Paulo

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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