Factors Affecting the Metabolite Productions in Endophytes: Biotechnological Approaches for Production of Metabolites-Reference-Cited by-同舟云学术

Factors Affecting the Metabolite Productions in Endophytes: Biotechnological Approaches for Production of Metabolites

Published:2020-04-23 Issue:11 Volume:27 Page:1855-1873
ISSN:0929-8673
Container-title:Current Medicinal Chemistry
language:en
Short-container-title:CMC

Author:

Morales-Sánchez Viridiana¹,Fe Andrés Maria¹,Díaz Carmen Elisa²,González-Coloma Azucena¹

Affiliation:

1. Instituto de Ciencias Agrarias, CSIC, Serrano 115-dpdo, Madrid 28006, Spain

2. Instituto de Productos naturales y Agrobiologia, CSIC. Avda. Astrofísico F. Sanchez, 3. 38206 La Laguna, Tenertife, Spain

Abstract

:Since 1980, many species and different strains from endophytic genera of Phomopsis, Fusarium, Pestaliopsis and Aspergillus have been studied because of their ability to produce medicinal compounds found in their host plants. Some of these medicinal agents such as Taxol, Brefeldine A, Camptothecin and Podophyllotoxin are being produced in large-scale after an optimization process. However, the potential of fungal endophytes to produce host-like medicinal compounds remains largely unexplored.

Funder

(MINECO/FEDER)

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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