Affiliation:
1. Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong University, Xi’an, China
2. Department of Spine Surgery, Xi’an Jiaotong University, Xi’an, China
Abstract
Tuberculosis, caused by Mycobacterium tuberculosis, is one of the oldest diseases
in the world and is one of the top ten causes of death in the world, ranking first mortality
in infectious diseases, far beyond the frightening disease AIDS. Besides that, spinal
tuberculosis is the most common form of extrapulmonary tuberculosis, accounting for approximately
1 to 3% of all tuberculosis cases, and accounting for 50% of musculoskeletal
infections. However, the drug-resistant situation of spinal tuberculosis is still challenging
world wide. This situation directly leads that spinal tuberculosis has a high disability rate
and is difficult to treat, which causes a heavy burden to patients, families and society.
Therefore, it has been one of the focuses of tuberculosis researchers and spine doctors.
Considering that, in this review, we aim to overview the current studies that focused on
the novel understanding of current spinal tuberculosis medicine usage and extensive explorations
for treating this severe disease.
Funder
Medical Research Project of Xi'an Science and Technology Bureau
Natural Science Research Plan in Shaanxi Province of China
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
7 articles.
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