Advances and Application of DNA-functionalized Nanoparticles-Reference-Cited by-同舟云学术

Advances and Application of DNA-functionalized Nanoparticles

Published:2020-01-03 Issue:40 Volume:26 Page:7147-7165
ISSN:0929-8673
Container-title:Current Medicinal Chemistry
language:en
Short-container-title:CMC

Author:

Zhang Xun¹,Wang Fei²,Sheng Jin-Liang³,Sun Min-Xuan¹

Affiliation:

1. Jiangsu Key Laboratory of Medical Optics, Chinese Academy of Sciences, Suzhou, China

2. Shanghai Tuberculosis Key Laboratory, Shanghai Pulmonary Hospital, Tongji University, Shanghai, China

3. College of Animal Science and Technology, Shihezi University, Shihezi, China

Abstract

DNA-functionalized nanoparticle (DfNP) technology, the integration of DNA with nanotechnology, has emerged over recent decades as a promising biofunctionalization tool in the light of biotechnological approaches. The development of DfNPs has exhibited significant potential for several biological and biomedical applications. In this review, we focus on the mechanism of a series of DNA-NP nanocomposites and highlight the superstructures of DNA-based NPs. We also summarize the applications of these nanocomposites in cell imaging, cancer therapy and bioanalytical detection.

Funder

Jiangsu Province Natural Science Foundation for Youths

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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