Affiliation:
1. Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, China
Abstract
The development of materials, chemistry and genetics has created a great number
of systems for delivering antibiotics, neuropeptides or other drugs to neurons in neuroscience
research, and has also provided important and powerful tools in neuron-related applications.
Although these drug delivery systems can facilitate the advancement of neuroscience studies,
they still have limited applications due to various drawbacks, such as difficulty in controlling
delivery molecules or drugs to the target region, and trouble of releasing them in predictable
manners. The combination of optics and drug delivery systems has great potentials to address
these issues and deliver molecules or drugs to the nervous system with extraordinary spatiotemporal
selectivity triggered by light. In this review, we will introduce the development of
photo-triggered drug delivery systems in neuroscience research and their neuron-related
applications including regulating neural activities, treating neural diseases and inducing nerve
regenerations.
Funder
Fok Ying-Tong Education Foundation
Basic Research Program of Shenzhen
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
9 articles.
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