Affiliation:
1. Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, Chengdu, Sichuan 610041, China
Abstract
Abstract:
Seven-membered heterocyclic compounds are important drug scaffolds because
of their unique chemical structures. They widely exist in natural products and show a variety
of biological activities. They have been used commonly in central nervous system
drugs in the past 30 years. In the past decade, many studies have been conducted on their
activities, including antitumor, antibacterial, etc. Herein, we summarize the research advances
in different kinds of seven-membered heterocyclic compounds containing nitrogen,
oxygen, and sulfur heteroatoms with antitumor, antisepsis, and anti-inflammation activities
in the past ten years, which are expected to be beneficial to the development and
design of novel drugs for the corresponding indications.
Funder
National Natural Science Foundation of China
Sichuan University–Lu Zhou Strategic Cooperation Projects
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
6 articles.
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