Affiliation:
1. Department of Chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran
2. Razi Chemistry
Research Center (RCRC), Shahreza Branch, Islamic Azad University, Isfahan, Iran
3. Department of Medicinal Chemistry, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran
Abstract
Abstract:
Sulfonamide compounds, also known as sulfa drugs, are a significant class of
synthetic bacteriostatic antimicrobials and were the primary source of therapy against bacterial
infections before the introduction of penicillin in 1941. Hybridization of sulfonamides
with various pharmaceutically active heterocyclic moieties leads to sulfonamide
hybrids with a wide variety of biological activities. Part B of this review presents the most
recent advances in designing and developing more two-component sulfonamide hybrids
containing triazole, thiadiazole, triazine, oxazole/ benzoxazole, isoxazole, oxadiazole, imidazole,
benzimidazole, furan, benzofuran, thiophene, pyrrole, indazole, tetrazole,
chromene/ chromone, pyridazine, quinoxaline, acridine, phthalazine, and xanthone between
2015 and 2020. We hope this review helps the scientific community in designing
more useful sulfonamide hybrid drugs.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
3 articles.
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