Affiliation:
1. College of Pharmaceutical Sciences, Institute of Life Science and Green Development, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Hebei University, Baoding 071002, China
Abstract
Respiratory viruses, including influenza virus, respiratory syncytial virus, coronavirus,
etc., have seriously threatened the human health. For example, the outbreak of severe
acute respiratory syndrome coronavirus, SARS, affected a large number of countries
around the world. Marine organisms, which could produce secondary metabolites with
novel structures and abundant biological activities, are an important source for seeking effective
drugs against respiratory viruses. This report reviews marine natural products
with activities against respiratory viruses, the emphasis of which was put on structures
and antiviral activities of these natural products. This review has described 167 marinederived
secondary metabolites with activities against respiratory viruses published from
1981 to 2019. Altogether 102 references are cited in this review article.
Funder
Hebei University Graduate Innovation Funding Project
Natural Science Interdisciplinary Research Program of Hebei University
China Postdoctoral Science Foundation
Scientific research Foundation of Hebei educational committee
National Natural Science Foundation of China
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry
Cited by
5 articles.
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