Current Scenario and Future Prospect in the Management of COVID-19

Author:

Borah Pobitra1ORCID,Deb Pran Kishore2ORCID,Deka Satyendra1ORCID,Venugopala Katharigatta N.3ORCID,Singh Vinayak4ORCID,Mailavaram Raghu Prasad5ORCID,Kalia Kiran6ORCID,Tekade Rakesh Kumar6ORCID

Affiliation:

1. Pratiksha Institute of Pharmaceutical Sciences, Chandrapur Road, Panikhaiti, Guwahati-781026, Assam, India

2. Department of Pharmaceutical Sciences, Faculty of Pharmacy, Philadelphia University, PO Box 1, Amman 19392, Jordan

3. Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia

4. Drug Discovery and Development Centre (H3D), University of Cape Town, Rondebosch, 7701, South Africa

5. Department of Pharmaceutical Chemistry, Shri Vishnu College of Pharmacy, Vishnupur, Bhimavaram – 534 202, West Godavari Dist., Andhra Pradesh, India

6. National Institute of Pharmaceutical Education and Research– Ahmedabad (NIPER-A), Opposite Air Force Station Palaj, Gandhinagar-382355, Gujarat, India

Abstract

: The COVID-19 pandemic continues to wreak havoc worldwide due to the lack of risk assessment, rapid spreading ability, and propensity to precipitate severe disease in comorbid conditions. In an attempt to fulfill the demand for prophylactic and treatment measures to intercept the ongoing outbreak, the drug development process is facing several obstacles and renaissance in clinical trials, including vaccines, antivirals, immunomodulators, plasma therapy, and traditional medicines. This review outlines the overview of SARS-CoV-2 infection, significant recent findings, and ongoing clinical trials concerning current and future therapeutic interventions for the management of advancing pandemic of the century.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmacology,Molecular Medicine,Drug Discovery,Biochemistry,Organic Chemistry

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