Affiliation:
1. Centro de Estudios Fotosinteticos y Bioquimicos (CEFOBI-CONICET), Universidad Nacional de Rosario, Suipacha 531, 2000, Rosario, Argentina
Abstract
Background:
Mitochondrial diseases are a complex group of pathologies caused by
mutations in genes coded in the nuclear and/or the mitochondrial DNA, which fulfill their function
in the organelle. The diagnosis is also complex, since it depends on the integration of biochemical,
histological and imaging data.
Objective:
In this paper we review the use of some of these substances and their efficacy in the
treatment of these disorders.
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Conclusions: Currently, there is not a fully effective treatment, however, it was demonstrated that
the use of some vitamins, amino acids, antioxidants along with a proper diet and exercise have an
important effect that leads to improve the overall state of patients with mitochondrial disorders.
Publisher
Bentham Science Publishers Ltd.
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