Copper-Catalyzed Cross-Coupling Between (E)-1,2-Diiodoethene and Carbazates: Entry to β-Functionalized N-Alkenylcarbazates
-
Published:2021-08-03
Issue:
Volume:18
Page:
-
ISSN:1570-1786
-
Container-title:Letters in Organic Chemistry
-
language:en
-
Short-container-title:LOC
Author:
Casault Paméla1ORCID,
Ricard Simon1ORCID,
Daoust Benoit1ORCID
Affiliation:
1. Département de Chimie, Biochimie et Physique, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, Canada
Abstract
:
The first intermolecular examples of copper-catalyzed cross-coupling between (E)-1,2-diiodoethene and various carbazates are reported here. (E)-β-iodovinylcarbazates were prepared with a complete retention of the olefin configuration. Favored regioisomer depends on the substrate’s structure. Subsequent functionalization of a model (E)-N-(β-iodovinyl)carbazate via cross-coupling reactions led to a variety of β-functionalized (E)-N-alkenylcarbazates with up to very good yields.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry