Affiliation:
1. Medical Informatics and Bioinformatics, Hochschule Ruhr West, University of Applied Sciences, Mülheim an der Ruhr,
Germany
Abstract
Abstract:
Diseases such as cancer are often defined by dysregulation of gene expression. Noncoding
RNAs (ncRNA) such as microRNAs are involved in gene expression and cell-cell communication.
Many other ncRNAs exist, such as circular RNAs and small nucleolar RNAs. A wealth of
knowledge is available for many ncRNAs, but the information is federated in many databases. A
small number of highly complementary ncRNA databases are discussed in this work. Their relevance
for cancer research is highlighted, and some of the current problems and limitations are revealed.
A central or shared database enforcing community reporting and quality standards is needed
in the future.
• RNA-seq
• Noncoding RNAs
• Databases
• Data repositories
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Biotechnology
Cited by
3 articles.
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