Bioactive Vitamins and Epigenetic Modifications in Diabetes: A Perspective-Reference-Cited by-同舟云学术

Bioactive Vitamins and Epigenetic Modifications in Diabetes: A Perspective

Published:2024-01 Issue:1 Volume:20 Page:
ISSN:1573-3998
Container-title:Current Diabetes Reviews
language:en
Short-container-title:CDR

Author:

Găman Mihnea-Alexandru¹²^ORCID,Cozma Elena-Codruța³⁴,Srichawla Bahadar S.⁵,Cozma Matei-Alexandru¹⁶,Kord Varkaneh Hamed⁷⁸,Chen Yongfeng⁹,Găman Amelia Maria¹⁰¹¹,Diaconu Camelia Cristina¹¹²

Affiliation:

1. Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, 8 Eroii Sanitari Boulevard, Bucharest 050474, Romania

2. Center of Hematology and Bone Marrow Transplantation, Fundeni Clinical Institute, 258 Fundeni Road, Bucharest 022328, Romania

3. Department of Dermatology, Elias Clinical Emergency Hospital, 15 Marasti Boulevard, Bucharest 011461, Romania

4. Doctoral School, University of Medicine and Pharmacy of Craiova, 2 Petru Rares Street, Craiova 200349, Romania

5. Department of Neurology, University of Massachusetts Chan Medical School. 55 Lake Ave N Worcester MA 01655, United States of America

6. Department of Gastroenterology, Colentina Clinical Hospital, 19-21 Stefan cel Mare Road, Bucharest 020125, Romania

7. Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran

8. Department of Nutrition and Food Hygiene, Nutritional Health Research Center, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

9. Department of Basic Medical Sciences, Medical College of Taizhou University, Taizhou, Zhejiang, 318000, China

10. Department of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

11. Clinic of Hematology, Filantropia City Hospital, 200143 Craiova, Romania

12. Internal Medicine Clinic, Clinical Emergency Hospital of Bucharest, 105402 Bucharest, Romania

Abstract

Abstract: Diabetes is a complex metabolic disease that has been associated with epigenetic changes. External factors such as dietary patterns can induce an imbalance in the pools of micronutrients and macronutrients in the body. Consequently, bioactive vitamins may influence epigenetic mechanisms via several pathways: involvement in the control of gene expression, and in protein synthesis, by acting as coenzymes and co-factors in the metabolism of methyl groups or methylation of DNA and histones. Herein, we present a perspective on the relevance of bioactive vitamins in the epigenetic modifications that occur in diabetes.

Publisher

Bentham Science Publishers Ltd.

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism