Affiliation:
1. Instituto de Investigaciones en Comportamiento Alimentario y Nutrición, Centro Universitario del Sur, Universidad de Guadalajara, Jalisco, Mexico
Abstract
Background:
Thousands of publications in recent years have addressed the induction of
metabolic syndrome (MetS) in rodents. However, the criteria and the reference values for diagnosing
this disease have not been defined.
Objective:
Our main objective was to carry out a systematic review to gather evidence about the criteria
for biochemical and anthropometric parameters in which scientific studies have relied on to report
that rats developed MetS from a previous dietary manipulation.
Methods:
We compiled characteristics and findings of diet-induced MetS with high-fat, high-carbohydrate,
high-fat/high-carbohydrates, and cafeteria diet from PubMed and Science Direct databases
published in the last 5 years.
Results:
The results on the principal determinants for the syndrome, published in the reviewed articles,
were chosen to propose reference values in the rat models of food induction.
Conclusion:
The values obtained will serve as reference cut-of points in the development of the disease;
in addition, the compilation of data will be useful in planning and executing research protocols
in animal models.
Funder
Consejo Nacional de Ciencia y Tecnología, CONACyT, México
Publisher
Bentham Science Publishers Ltd.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献