Antiplatelet and Antithrombotic Therapy in Type I Diabetes Mellitus: Update on Current Data

Author:

Maragkoudakis Spyridon1,Katsi Vasiliki2,Melidonis Andreas3,Soulaidopoulos Stergios4,Kolovou Genovefa D.5,Papazafeiropoulou Athanasia K.6,Trikkalinou Aikaterini3,Toutouzas Konstantinos4,Tsioufis Konstantinos4

Affiliation:

1. Cardiology Department, General Hospital of Chania, Chania, Greece

2. First Department of Cardiology, National and Kapodistrian University of Athens,School of Medicine, Hippokration General Hospital, Athens, Greece

3. Diabetes Center, Metropolitan Hospital Athens, Athens, Greece

4. Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece

5. Cardiometabolic Center, Lipid Center, Metropolitan Hospital, Athens, Greece

6. Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, Piraeus, Greece

Abstract

Abstract: Diabetes mellitus type 1 (T1DM) is an autoimmune disease characterized by a markedly elevated cardiovascular (CV) risk due to premature atherosclerosis. Previous studies have shown that intense glycemic control reduces the incidence of CV disease. Antiplatelet therapy is considered to be a very important therapy for secondary prevention of recurrent atherothrombotic events in patients with DM, while it may be considered for primary prevention in individuals with T1DM with additional CV risk factors. The aim of the present review is to summarize existing literature data regarding the thrombotic risk in T1DM patients and discuss current treatment strategies.

Publisher

Bentham Science Publishers Ltd.

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

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