Is There a Relation between Hypothyroidism and Polycystic Ovary Syndrome and its Metabolic Components?

Abstract

Objective: The purpose of this research was to evaluate the incidence of hypothyroidism in PCOS patients compared with healthy control groups, as well as the impact of hypothyroidism on metabolic parameters, particularly insulin resistance, in PCOS patients. Method: Forty-one women with PCOS criteria and 41 healthy women as controls was selected. From March to November 2018, sick and healthy people were randomly. Participants' demographic information was gathered. Between the case and control groups, thyroid function tests were compared. Metabolic parameters were examined between hypothyroid and euthyroid PCOS individuals. Results: Patients with PCOS showed a greater incidence of hypothyroidism and higher level of anti-TPO than control group. HDL cholesterol was substantially greater in hypothyroid PCOS patients than in non-hypothyroid individuals, although there were no significant changes in other metabolic markers. Insulin resistance was comparable in PCOS patients with hypothyroidism and those who did not. Autoimmunity was not linked to a higher risk of metabolic problems. Conclusion: We found that PCOS patients had a higher prevalence of subclinical hypothyroidism compared with healthy subjects. Metabolic indicators, with the exception of HDL, were not different between PCOS patients with and without hypothyroidism.