Affiliation:
1. Pharmacology Division, Faculty of Pharmacy, Rhodes University, Grahamstown, South Africa
2. School of Laboratory Medicine and Medical Sciences, College of Health Sciences, Durban, South Africa
Abstract
Background:
Diabetes mellitus and prediabetes have been shown to be associated with
high rates of developing severe COVID 19 complications resulting in morbidity and mortality.
Emerging reports suggest that COVID 19 is associated with glycaemic control aberrations, although
the extent is not clear at present. Accordingly, in this review, the efforts are directed to shed
light on why we can anticipate an increase in diabetes cases amid or post-COVID 19 pandemic.
Methods:
Articles reviewed were identified using the Google Scholar database, and the search was
done using the English language.
Results:
Previous studies have shown that viral inflammation triggers insulin resistance, which can
progress to overt diabetes. SARS-CoV-2 has also been shown to cause acute pancreatitis, which
can increase the risk of developing diabetes mellitus. The control of the COVID 19 pandemic partly
relied on non-pharmaceutical measures, which included lockdowns. This resulted in a lack of
physical activity and unhealthy eating behaviour, which could contribute to obesity and, ultimately,
insulin resistance.
Conclusion:
While no concrete data has been established on the possibility of seeing an increase in
diabetes prevalence due to COVID 19, studies are necessary to establish the link. Despite the unavailability
of data at present, we suggest that frequent screening of diabetes and prediabetes should
be encouraged, especially in those individuals with a history of COVID 19 infection.
Funder
National Research Foundation South Africa
Publisher
Bentham Science Publishers Ltd.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
3 articles.
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