Affiliation:
1. Family Medicine, Kanad Hospital, Al Ain, United Arab Emirates
2. Department of Family Medicine, United Arab Emirates
University College of Medicine and Health Sciences, Al Ain, UAE
3. Department of Family & Geriatric Medicine,
University of Louisville, Louisville, KY, U.S.A
Abstract
Objective:
Muslims with insulin-dependent type 2 diabetes are at high risk for adverse
events while fasting during the month of Ramadan. However, advances in pharmacologic therapy
coupled with creative strategies of insulin administration can mitigate complications. This narrative
literature review investigates which insulin subtypes are likely to prevent hypoglycemic events and
reduce hyperglycemia during the Ramadan fasting season for this high-risk population.
Design:
Narrative literature review
Eligibility Criteria:
The following MeSH terms were used: “Diabetes Mellitus, Type 2” and “Insulin,”
and the “Text Words”: “Ramadan”, “iftar”, “Muslim fast”, and “religious fast.” The primary
focus was on adult, non-pregnant, insulin-dependent type 2 diabetes during Ramadan. Anything
beyond this focus was excluded. A total of nine pertinent studies were included for narrative review
and analysis.
Information Sources:
PubMed, EMBASE and Medline.
Results:
The studies identified suggest long-acting insulins reduce the risk of hypoglycemia, and
rapid-acting insulin analogues may improve post-iftar hyperglycemia. Moreover, utilizing flexible
glycemic targets during Ramadan is a novel strategy that has demonstrated improved outcomes after
the fasting season.
Conclusion:
Certain insulin subtypes and dosing strategies may be advantageous to use during
Ramadan. However, a systematic, comprehensive, and updated review, including a critical appraisal
of each original study, is needed to improve clinical care of insulin-dependent type 2 diabetes
during Ramadan.
Publisher
Bentham Science Publishers Ltd.
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献